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Protocolos
Experimental reference

Peptides, nootropics and related compounds — in English, with the limits of the evidence in plain view.

86 compounds and combinations — from peptides to nootropics, SARMs, and what exists registered in Brazil —, with dose, reconstitution, cycle structure, and regulatory status. Each page separates what a published trial tested from what is merely community-reported practice, because the difference between the two is the whole subject. In 29 of them the figures did not come from a secondary source: they were checked against PubMed, ClinicalTrials.gov, and the package insert — with the query declared on each page, for you to repeat and contradict me.

29 pages with the figure verified by me in PubMed, the package insert and ClinicalTrials.gov — with the query declared in each one
57 pages with the dose carried over from a commercial secondary source and translated, without my having checked the figure at the origin

The difference between the two is printed on every table of this site: where the figure was verified, the table carries a ruler on its edge and the value is set in a different typeface. Where it was not, it carries nothing.

Experimental material. Read before using anything from here.

Nothing on this page is a medical recommendation, prescription or treatment plan. It is an organized translation of protocols circulating in research communities and, where it exists, of what published trials tested. The two are marked differently — and they are not equivalent.

Most of the compounds here have no FDA approval for human use. Several are sold labeled "research use only", which means they have not gone through purity, sterility or dosage controls for human consumption. A community-reported dose is not a validated dose: it is what someone reported having done.

Talk to a licensed health professional before considering any of these compounds. If you already use one and feel anything unexpected, seek care — do not wait for the next routine test.

Nootropics

The site was born from peptides, but the most consulted part today is this one — and they are two different questions, on two pages. How many trials exist is not the same thing as what they found.

The filter is a shortcut, not a gate. The 87 compounds are listed and linked below, grouped by section — you can reach any of them by scrolling the page, without searching.

The registration badge comes from the scan of open data done on September 4, 2026, and appears only on the 44 compounds that were measured one by one. Combinations and method pages have no badge.

Repair and tissue

Compounds studied in wound healing, tendon, skin and local inflammation.

Metabolic and weight

Incretin agonists and related compounds studied in weight and glycemia.

Growth hormone axis

GHRH analogs and secretagogues that ask the body itself to release GH.

Neuro and cognition

Compounds studied in attention, memory, anxiety and sleep.

Longevity and mitochondria

Targets linked to senescence, NAD+ and mitochondrial function.

Hormonal and sexual

Reproductive axis, libido, pigmentation and vasodilation.

Immune

Modulation of the immune response.

Combinations

Protocols that combine two or more compounds in the same cycle.

Verified against primary sources

Pages built directly from PubMed and ClinicalTrials.gov, not from the secondary source. They carry the evidence count and the query used.

Dose adjustment for hepatic function

Partially approved

Here it is not just a gap: there is documented harm, with numbers and outcomes — and it hits exactly the people this site attracts

Verified against primary sources5 table(s)

Dose adjustment for renal function

Partially approved

Where the data exist, the package insert says not to adjust anything — and the real risk sits three sections up, in an item almost nobody reads

Verified against primary sources2 table(s)

Monoclonal antibodies

Partially approved

Thirty-five times heavier than a peptide, made by a living cell and given by intravenous infusion — of the three that come up in the body-composition conversation, only one has a label

Verified against primary sources4 table(s)

Khavinson short bioregulators

Not approved

Eleven peptides, five clinical studies, zero registered trials

Verified against primary sources2 table(s)

CRISPR

Partially approved

Out of 64,641 articles, 67 are clinical trials and 1 became a drug — and what limits that drug is not the gene editing, it is the chemotherapy around it

Verified against primary sources11 table(s)

Baldness — the old and what's coming

Partially approved

Eighteen treatments measured on the same yardstick: minoxidil has 23 active registrations as an anti-baldness treatment, and PP405, which circulates as a research powder, has 1 article on PubMed

Verified against primary sources3 table(s)

Casgevy

Partially approved

The declared bottleneck is not the price — in England there are 1,794 eligible patients and 23 treatments in the first year, and the reason the assessor writes down is hospitalization, not cost

Verified against primary sources9 table(s)

Kidney disease

Partially approved

From zero to six drugs in four and a half years — and five of them were approved on a number that is not the one that matters to the patient

Verified against primary sources5 table(s)

Exosomes

Not approved

45,674 articles, 83 randomized trials, and no product approved by any agency

Verified against primary sources2 table(s)

Liver and lipids

Partially approved

Thirteen molecules with two-digit PubMed article counts and outcome trials of up to 17,300 participants — and only one of them, inclisiran, has active registration

Verified against primary sources3 table(s)

Geroprotectors

Partially approved

Seventeen candidates to delay aging: 6 don't have a single registered phase 3 trial, and 8 of the 13 active ingredients searched have no active registration

Verified against primary sources3 table(s)

Next-generation incretins and amylins

Partially approved

Thirteen molecules competing for semaglutide's spot — 11 already have a registered phase 3, and 9 of the 11 with a published INN have not a single active registration

Verified against primary sources3 table(s)

Prescription-only items from the list

Partially approved

13 drugs that appeared mixed in with supplements

Verified against primary sources2 table(s)

KLOW — the evidence

Not approved

The blend still has no trial, but three components entered clinical phase in 2026

Verified against primary sources2 table(s)

Mazdutide

Not approved

12 phase 3 trials, published in NEJM, JAMA and Nature — and no package insert

Verified against primary sources2 table(s)

Eastern European drugs

Partially approved

18 imported drugs, 29 registered trials — and a forgotten history of deaths

Verified against primary sources3 table(s)

Meldonium (mildronate)

Partially approved

357 articles, 7 registered trials — and a detection window of months

Verified against primary sources4 table(s)

Muscle, bone, HPG axis and immune system

Partially approved

Fifteen molecules that peptide chatter cites as though they were equivalent to research vials — 6 of the 14 searched have active registration, with a declared commercial name and therapeutic class

Verified against primary sources3 table(s)

Neuro and cognition — the Russian bloc and what has a label

Partially approved

Noopept, phenylpiracetam, bromantane, and cortexin together have 0 registered studies on ClinicalTrials.gov; lecanemab and donanemab already have active registration

Verified against primary sources3 table(s)

Nootropics

Partially approved

32 with human evidence, 12 with no trial at all — and four counts that were inflated

Verified against primary sources3 table(s)

The GH axis outside the peptide vial

Partially approved

The recombinant hormone has 54,472 articles, 183 phase 3 trials, and 9 active registrations; the secretagogues the community uses instead have zero active registrations

Verified against primary sources3 table(s)

The GLP-1s against the package insert

Partially approved

The doses were right. The black box warning was missing

Verified against primary sources6 table(s)

Repair beyond BPC and TB-500

Not approved

Thymosin β-4 has 4 phase 3 trials — and they are for dry eye drops, not muscle repair; AHK-Cu has 1 article on PubMed

Verified against primary sources3 table(s)

SARMs

Not approved

Half of the products sold as SARMs do not contain the SARM on the label — and four of the most popular have never had a clinical trial

Verified against primary sources8 table(s)

Semax — the evidence

Partially approved

The dose in the Russian trials is 12 to 72 times the community's

Verified against primary sources2 table(s)

Effect size

Partially approved

How many trials exist is one question; what they found is another — 34 meta-analyses opened

Verified against primary sources3 table(s)

Thymalin

Partially approved

Russian thymic extract — 293 articles, 13 trials, zero trial registrations

Verified against primary sources2 table(s)

Treatments that aren't a substance

Partially approved

Five procedures that compete with this site's vials and add up to 69,593 articles on PubMed and 5,349 registered studies

Verified against primary sources2 table(s)

Alcohol and steatosis

Partially approved

The underlying cause no liver panel sees — and one that multiplies, rather than adds to, the risk of everything else you take

Verified against primary sources6 table(s)

Supplements and related compounds

Over-the-counter items, with the dose range used in studies. Kept separate from those that require a prescription.